【Batch】Synthesis of organic anion transporting polypeptide imaging agent (Suzuki coupling) 【バッチ】有機アニオントランスポーターイメージング剤の合成（鈴木カップリング反応）
Org. Biomol.Chem., 13, 1113-1121 (2015).

Outline

Org. Biomol.Chem., 13, 1113-1121 (2015).
DOI: 10.1016/j.tetlet.2022.154010

“The synthesis of [18F]pitavastatin as a tracer for hOATP using the Suzuki coupling”

Yagi Y ^a , Kimura H ^a,b , Arimitsu K ^a,c , Ono M ^a , Maeda K ^d , Kusuhara H ^d , Kajimoto T ^e , Sugiyama Y ^e,f , Saji H ^a .

^a Department of Patho-Functional Bioanalysis, Graduate School of Pharmaceutical Sciences, Kyoto University, Kyoto, Japan
^b Radioisotope Research Center of Kyoto University, Kyoto, Japan
^c School of Pharmaceutical Sciences, Mukogawa Women’s University, Hyogo, Japan
^d Laboratory of Molecular Pharmacokinetics, Graduate School of Pharmaceutical Sciences, The University of Tokyo, Tokyo, Japan
^e Research Organization of Science and Technology, Research Center for Drug Discovery and Pharmaceutical Development Sciences, Ritsumeikan University, Shiga, Japan
^f Sugiyama Laboratory, RIKEN Innovation Center, RIKEN Research Cluster for Innovation, RIKEN, Yokohama, Japan

Equipment information Reactor size: batch-type microwave reactor, Maximum power: 10 W (SAIDA FDS INC.)

概要

実験結果提供：
京都大学　屋木 祐亮先生⁑、木村 寛之先生⁑、有光 健治先生、小野 正博先生、佐治　英郎先生*
東京大学　前田 和哉先生、楠原博之先生
立命館大学　梶本 哲也先生
理化学研究所　杉山 雄一先生