静岡大学とサイダ・FDSの研究成果がThe Chemical Record誌に掲載されました

静岡大学 間瀬暢之先生、武田和宏先生、佐藤浩平先生によるサイダ・FDS装置を使った研究成果がThe Chemical Record誌(https://doi.org/10.1002/tcr.201800048)に掲載されました。

Title
Rapid Optimization of Reaction Conditions Based on Comprehensive Reaction Analysis Using a Continuous Flow Microwave Reactor

Authors
Péter Vámosi  Keiya Matsuo  Tsuguya Masuda  Dr. Kohei Sato  Dr. Tetsuo Narumi Dr. Kazuhiro Takeda  Dr. Nobuyuki Mase

(反応例:アルコールのアセチル化 大量合成)

Abstract
 Generally, the flow method has the advantage of a precise control over the reaction parameters and a facile modification of the reaction conditions, while a continuous flow microwave reactor allows for the quick optimization of reaction conditions owing to the rapid uniform heating. In this study, we developed a “9+4+1 method” to optimize reaction conditions based on comprehensive reaction analysis using a flow microwave reactor. The proposed method is expected to contribute to the synthesis of various fine and bulk chemicals by reducing cost and wastage, and by conserving time.