静岡県立大学とサイダ・FDSの研究成果がMolbank誌に掲載されました

2018年05月12日静岡県立大学とサイダ・FDSの研究成果がMolbank誌に掲載(http://www.mdpi.com/1422-8599/2018/2/M996/)されました。
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Title
(E)-3-[4-(Pent-4-en-1-yloxy)phenyl]acrylicc Acid

Authors
Hiromichi Egami , Taira Sawairi, Souma Tamaoki, Noriyuki Ohneda, Tadashi Okamoto, Hiromichi Odajima and Yoshitaka Hamashima

Molbank 20182018(2), M996
(https://doi.org/10.3390/M996)

Abstract
  (E)-3-[4-(Pent-4-en-1-yloxy)phenyl]acetic acid is one of the useful components of liquid crystal materials which can be produced through Williamson ether synthesis by synthesizing 4-hydroxy-cinnamic acid and 5-bromo-1-pentene. Although Williamson ether synthesis is generally slow under conventional external heating conditions, microwave irradiation was effective for significant acceleration of the etherification. Furthermore, we demonstrated the rapid and continuous synthesis of (E)-3-[4-(pent-4-en-1-yloxy)phenyl]acetic acid, using a microwave-assisted flow reactor developed by us, in which the blockage by salt precipitation was suppressed by the continuous addition of an aqueous methanol solution after the reaction cavity.